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AIDS & CANCER - A DISSENTING VIEWA Modern Day Copernicus - Peter H. DuesbergBy Donald W. Miller, Jr., MD Posted on www.lewrockwell.com February 23, 2006
The AIDS virus [HIV] also proved to be the politically correct cause of AIDS. No AIDS risk groups [e.g., gay men] could be blamed for being infected by a God-given egalitarian virus. A virus could reach all of us. Nobody would be ostracized since 'We are all in this together.' Not so with drugs. The consumption of illicit psychoactive drugs implies individual and social responsibilities that nobody wanted to face The perceived danger of an AIDS virus decimating the general public also provided the scientific and moral arguments for quick and unreflective action and for the complete dismissal of the competing drug-AIDS hypothesis.Pope Clement VII encouraged Copernicus to publish his work, and On the Revolutions of the Heavenly Spheres is dedicated to his successor, Pope Paul III. The Catholic Church supported his research, but Martin Luther and other Protestant reformers denounced it. The Holy See accepted Copernicus' heliocentric system as a hypothesis, one which made determining holy days, Easter in particular, easier. Galileo (1564-1642) subsequently mounted a "Copernicus Crusade" and proclaimed the hypothesis a fact, which compelled the Church to excommunicate him, an action it now regrets. It was appropriate, however, to treat Copernicus' heliocentric system as a hypothesis, which has turned out not to be entirely true. We now know the sun is not stationary but rotates around the center of the Milky Way Galaxy with its planets in tow. Kary Mullis, who won the Nobel Prize in 1993 for inventing the polymerase chain reaction, now used to measure HIV "viral load," states in his book Dancing Naked in the Mind Field (1998), "Years from now, people will find our acceptance of the HIV theory of AIDS as silly as we find those who excommunicated Galileo." While Duesberg continues to be vilified for his contrarian view of AIDS, investigators are increasingly willing to consider his equally contrarian view of cancer. Chapter Six of Bialy's Oncogenes, Aneuploidy, and AIDS: A Scientific Life & Times of Peter H. Duesberg deals with this subject and is titled "The Phoenix Almost Rises." The media do not report his work on cancer so as not to "legitimize" him. (The New York Times has made no mention of it.) One exception is Scientific American. It published an article in its July 2003 issue titled * "Untangling the Roots of Cancer" written by one of its senior writers. The article lists, in a timeline illustration, the 12 most important events in the evolution of cancer theory over the last 100 years. Number 10 in this list, occurring in 1999, is: "Peter Duesberg publishes detailed theory of how aneuploidy may be sufficient to cause cancer itself, even without mutations to any particular sets of genes." Normal human cells have 46 chromosomes, 23 from each parent. They are euploid (contain the correct number of chromosomes). Aneuploidy means the cell has an abnormal number and balance of chromosomes (strands of DNA consisting of many genes and other elements), either too many or too few. All solid tumor cancer cells have an abnormal number of chromosomes, usually ranging from 60 to 90. Colon cancer cells contain an average of 79 chromosomes. Cells that have an abnormal number of chromosomes can become cancerous by constantly altering their number and composition in succeeding generations of cells until at some point, perhaps decades later, one of these genetically unbalanced cells turns malignant. And since aneuploidy is inherently unstable, cancer cells continually spawn new cells with differing numbers and assortments of chromosomes and therefore a unique genetic makeup (karyotype). This enables the cancer to survive when threatened by chemotherapy and radiation because a subpopulation of its cells becomes genetically resistant to these challenges. The aneuploidy cancer hypothesis better explains why these treatments offer only a remission (while the surviving subpopulation regroups) and not a cure for cancer. This hypothesis shifts the focus to on how to prevent cancer rather than trying to find a cure. Three important papers Duesberg has written on this subject, with private support, are * "How Aneuploidy Affects Metabolic Control and Causes Cancer (1999)," with David Rasnick; * "Aneuploidy, the Somatic Mutation that Makes Cancer a Species of Its Own (2000)," with Rasnick; and "Aneuploidy, the Primary Cause of the Multilateral Genomic Instability of Neoplastic and Preneoplastic Cells (2004)," with Alice Fabarius and Ruediger Hehlmann. Postulating a viral etiology for most cancers, the "War on Cancer" launched by President Nixon in 1971 focused on viruses, with the prospect of a viral anti-cancer vaccine to come. When this line of investigation went nowhere, in the 1980s the virus-centered system of cancer morphed into a virus-centered view of AIDS; and the gene mutation hypothesis superseded viruses as the cause of cancer. Now Duesberg, in Copernican fashion, is replacing the genocentric (gene-centered) model of cancer with aneuploidy. This paradigm shift in understanding cancer, the second most common cause of death in our species, will have far-reaching consequences. The incidence of cancer in the U.S. has more than doubled over the last century. Newer treatment modalities, such as chemotherapy and radiation, have provided little, if any, benefit in (long-term) survival rates. The aneuploidy-centered system of cancer explains why it has been so difficult to find a cure for cancer, and research dollars would be better invested seeking ways to prevent it. Studies on environmental triggers - carcinogens and nutritional factors - that foster aneuploidy need to be funded and done. When Duesberg's work on HIV/AIDS and cancer is finally recognized and accepted, it will cause a revolution in science. Over the last 50 years government-sponsored and industry-sponsored research programs have come to dominate scientific research. A totalitarian system now exists where only scientists that adhere to the prevailing orthodoxy can receive funds to conduct research. Not only will the government not fund studies on alternative hypotheses for AIDS and cancer, but this stricture applies to other areas of inquiry. All research on climate change must conform to the dogma of human-caused global warming, and studies on vaccines dare not criticize their safety or efficacy. No government grants will be awarded to anyone who wants to study radiation hormesis - and question the linear no-threshold hypothesis. Studies published that support the reigning dogma are riddled with conflicts of interest, manipulated statistics, and bias. Once the HIV-AIDS hypothesis is acknowledged to be false, a domino effect will impact other branches of science that government now controls. Academic leaders in the inner circle of the medical-industrial-government complex will be called to account. Industry will likely face lawsuits. And government agencies, particularly the NIH, CDC (Centers for Disease Control and Prevention), and FDA (Food and Drug Administration) will have a lot to answer for. Duesberg's work will do to biology and science in this century what Copernicus did to astronomy and science five centuries ago. In an interview conducted by the Berkeley Science Review, Peter Duesberg was asked, "If you could live your career again, would you change anything?" His reply: "I would possibly be more diplomatic than I was, when I first discovered the many paradoxes of the virus-AIDS hypothesis and of the now-prevailing gene mutation hypothesis of cancer. But I would not be a scientist who ranks acceptance by the mainstream higher than scientific discovery. Since we all live only once I would rather be respected by the next generation for a lasting scientific contribution, than by the current one for work that is popular now but scientifically flawed." For the 200,000 healthy, HIV-positive Americans who must take DNA chain terminators based on the belief that HIV causes AIDS, and the one out of every three Americans who will get cancer, one hopes that Peter Duesberg's work will be recognized and accepted soon. More than 2,000 scientists, medical professionals, authors, and academics have now gone on record doubting the HIV/AID hypothesis. Their comments are catalogued here. People who read Harvey Bialy's beautifully written book about Duesberg, especially scientists, will come away with a new view of oncogenes, aneuploidy, and AIDS. Donald Miller (send him mail) is a cardiac surgeon and Professor of Surgery at the University of Washington in Seattle. He is a member of Doctors for Disaster Preparedness and writes articles on a variety of subjects for LewRockwell.com. His web site is www.donaldmiller.com
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